Ascorbyl‐6‐O‐oleate: A Bioconjugate Antioxidant Lipid

Antioxidant Vitamins and Lipid Therapy

During the past decade, the perception flourished that lipid and antioxidant therapy were 2 independent avenues for cardiovascular protection. However, studies have shown that commonly used antioxidant vitamin regimens do not prevent cardiovascular events. We found that the addition of antioxidant vitamins to simvastatin-niacin therapy substantially blunts the expected rise in the protective hi...

Antioxidant activity and lipid peroxidation in preeclampsia.

BACKGROUND Epidemiologic studies demonstrate a relation between preeclampsia and an increased risk of future maternal coronary heart disease. The pathophysiology of the underlying mechanism is unknown. Disorders of lipoprotein metabolism may contribute to endothelial dysfunction. Oxidative stress and decreased antioxidant defense enhances free radical-mediated membrane lipid peroxidation and po...

A lipid-soluble antioxidant from polyallomer centrifuge tubes.

Santowhite, a commercial antioxidant used in the manufacture of polypropylene, contaminates 12-ml polyallomer tubes to the extent of 0.2-0.3 mg/tube. It is distributed through the plastic and appears as a microscopic dust on the tubes' surfaces. In the preparation of polysomes from rat liver by standard methods, approximately 15% of the antioxidant in previously water-washed tubes was removed b...

Lipid peroxidation and antioxidant status in preeclampsia: a systematic review.

BACKGROUND Preeclampsia is characterized by increased lipid peroxidation and diminished antioxidant capacity; however, there is no consensus as to the extent of these conditions. OBJECTIVE To assess the association of lipid peroxidation and antioxidant status with preeclampsia quantitatively using meta-analysis. DESIGN Systematic review and meta-analysis. SEARCH STRATEGY Studies were iden...

Bioconjugate Therapeutics: Current Progress and Future Perspective.